So to circle back on this, Edward was able to get this resolved actually with the help of another OAK user. I tried to help over email but was not much help relative to the other user. The issue is particular to macOS 10.13.
The solution is:
step1: brew install libusb
step 2: python3 -m pip install depthai
step 2.5: python3 install_requirements.py
step 3: then trash the just installed palace.dylibs/libusb-1.0.0.dylib
step 4: create a symlink in its place to the libusb-1.0.0.dylib
created in the first step.
It appears that the install script in step 2 is the real cause of this problem; that is, it is installing a 10.15 version of libusb-1.0.0.dylib. So this is why deleting what it installs, and using what brew installs from the first step is what fixes it.
(And thanks EdW for having circled back with the solution.)
Best,
Brandon